Mitomycin Impurity 7 Trifluoroacetate CAS 99745-88-7 (free base)
| CAS No. | 99745-88-7 (free base) |
| Molecular Formula | C14H16N4O5 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Mitomycin Impurity 7 Trifluoroacetate (C14H16N4O5C2HF3O2) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Mitomycin Impurity 7 Trifluoroacetate (CAS 99745-88-7 (free base), C14H16N4O5C2HF3O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Mitomycin Impurity 7 Trifluoroacetate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H16N4O5 C2HF3O2 |
| Molecular Weight | 434.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Mitomycin Standards
- Mitomycin D (CAS 10169-34-3)
- Mitomycin EP Impurity D (CAS 111750-67-5)
- Mitomycin Related Compound 6 Trifluoroacetate (Mixture of Diastereomers) (CAS 1192552-64-9 (free base))
- Mitomycin Impurity A (trans-Cinnamamide) (CAS 22031-64-7)
- Mitomycin EP Impurity B (Mitomycin A) (CAS 4055-39-4)
- Mitomycin EP Impurity C (CAS 4055-40-7)
- Mitomycin C (CAS 50-07-7)
- Mitomycin impurity 5 (CAS 98462-75-0)
Recommended Standards
- Relebactam Impurity 74 (CAS CATO-C4X-214474)
- Itopride Impurity 19 (CAS 15182-92-0)
- Clopidogrel Impurity N1 (CAS 85567-51-7)
- N-Methyl-2-nitro-N-phenylaniline (CAS 52997-62-3)
- 1-(Pyridin-2-yl)propan-2-one (CAS 6302-02-9)
- (E)-1-(1-(4-methyl-6-(trifluoromethyl)pyrimidin-2-yl)-1H-1,2,3-triazol-4-yl)-3-(thiophen-2-yl)prop-2-en-1-one (CAS 861211-63-4)
- 4-Methyl-3-(pentyloxy)benzaldehyde (CAS 1443304-64-0)
- Tenovin-2 (CAS 666211-30-9)
- SASRIN? resin (200-400 mesh, 0.80-1.20 mmol/g) (CAS 124760-64-1)
- Neuropeptide Y (free acid) (human, rat) trifluoroacetate salt (CAS 99575-89-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com